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Guide Genetic Effects on Environmental Vulnerability to Disease (Novartis Foundation Symposia)

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Role of gene-stress interactions in gene-finding studies Snieder, H. Novartis Foundation Symposium; vol. Single Nucleotide Polymorphism. Gene-Environment Interaction. Prostasin: A possible candidate gene for human hypertension Zhu, H.

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TUB is a candidate gene for late-onset obesity in women Snieder, H. Abdominal Obesity. Waist Circumference. Weights and Measures. Age Distribution. Animal Models.

Vascular Stiffness. Pulse Wave Analysis. Apolipoproteins B. Phosphatidylinositol 3-Kinases. LDL Cholesterol. Common polymorphisms in SOCS3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins Jamshidi, Y. Body Weight. Gene Frequency. Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth Wang, X. Angiotensin I.


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Angiotensin Receptors. Dopamine Receptors.

Protein Subunits. Erratum: Genetic and environmental determinants of lipid profile in Black and White youth: A study of four candidate genes Ethnicity and Disease 15, 4, Davis, C. Ethnic and gender differences in ambulatory blood pressure trajectories: Results from a year longitudinal study in youth and young adults Wang, X.

Cross-Sectional Studies.

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Ethnic differences in heart rate variability: Does ultralow-frequency heart rate variability really measure autonomic tone? Thayer, J. Autonomic Nervous System. Ethnic Groups. Research Design. Phosphatidylinositol 3-Kinase. Regulator Genes.


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Adipose Tissue. Plasminogen activator inhibitor-1 gene selection of tagging single nucleotide polymorphisms and association with coronary heart disease Su, S. Plasminogen Activator Inhibitor 1. Coronary Disease. The Georgia Cardiovascular Twin Study: Influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes Ge, D. Twin Studies. Type 2 Diabetes Mellitus. Cardiovascular Diseases. The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins Zhu, H.

G-Protein-Coupled Receptor Kinase 4.

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The G protein-coupled receptor kinase 4 gene modulates stress-induced sodium excretion in black normotensive adolescents Zhu, H. Video Games. Update on G-protein polymorphisms in hypertension Zhu, H. GTP-Binding Proteins. Pertussis Toxin. Body Size. Body Mass Index. Waist-Height Ratio. Multigene Family. One of the tenets emerging from a cumulative body of research is that in neuroimaging, as in life, the journey is often as important as the destination. Assessing the trajectories i. These findings may imply that different brain regions may be more susceptible to environmental interventions at some times than others.

Although there is a trend toward an increasing number of people, training programs, journals and funding directed toward research of adolescent neurobiology, historically it has been relatively understudied. One aspect of adolescent decision making that has been targeted for future research is to characterize the distinctions between traditional laboratory assessment done with subjects acting alone in low-stress testing environments with hypothetical scenarios i.

Another research challenge is to deepen our understanding of the relationship between neuroimaging findings and specific cognitive abilities or psychological characteristics. As mental functions arise from the activity of distributed neural networks, the practice of attempting to correlate the size of any single structure with a particular ability is giving way to the recognition of the need to understand the complex relationships amongst different nodes of the networks.

Mathematical approaches such as graph theory are beginning to be used to explore the network properties of the brain. A fundamental aspect of adolescent brain maturation is that it is a time of dramatic change. The plasticity of the human adolescent brain makes adolescence a time of great risk and great opportunity. Despite the temptation to trade the complexity and ambiguity of human behaviour for the clarity and aesthetic beauty of colorful brain images, we must be careful not to over-interpret neuroimaging findings as they relate to public policy.

Age-of-consent questions are particularly enmeshed in political and social contexts.

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For example, currently in the United States a person must be at least 15 to 17 years old depending on the state to drive, at least 18 to vote, buy cigarettes or be in the military, and at least 21 to drink alcohol. The minimum age for holding political office varies as well: some municipalities allow mayors as young as 16, and the minimum age for governors ranges from 18 to On the national level, 25 is the minimum age to be a member of the U.

House of Representatives, and 35 to be a senator or the President. The age of consent to sexual relations varies worldwide from puberty with no specific age attached to age Giedd JN. Adolescent Brain Maturation.

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Paus T, topic ed. Encyclopedia on Early Childhood Development [online]. Published November Accessed September 25, Skip to main content. Back to recent texts Adolescent Brain Maturation.

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PDF version. Introduction The teen years have long been noted as a time of dramatic changes in body and behaviour. Subject Most teenagers successfully navigate the transition from the dependency of childhood to the self-sufficiency of adulthood. Problems Although adolescence is a time when many major life decisions are made and societies grant broader freedoms and responsibilities, surprisingly little research has been done to explore how changes in cognition, emotion and behaviour affect the decision-making processes.